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mRNA expression of PARP1 in SCLC cell lines and solid tumors.

Published bySugiarto Atmadja Modified over 5 years ago

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Presentation on theme: "mRNA expression of PARP1 in SCLC cell lines and solid tumors."— Presentation transcript:

1 mRNA expression of PARP1 in SCLC cell lines and solid tumors.
mRNA expression of PARP1 in SCLC cell lines and solid tumors. A, mRNA expression in SCLC (green) and NSCLC cell lines (pink) for genes corresponding to the total proteins dysregulated in SCLCs. B, potentially druggable targets identified by RPPA that were also more highly expressed at the mRNA level in SCLCs included PARP1, EZH2, Bcl-2, PRKDC (DNA PKcs), and PCNA. C, PARP1 mRNA expression was higher in SCLC cell lines than in other solid tumor cell lines. D, mRNA expression of potential drug targets was higher in SCLC tumors than in NSCLC tumors or normal lung. SCC, squamous cell carcinoma. Lauren Averett Byers et al. Cancer Discovery 2012;2: ©2012 by American Association for Cancer Research

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