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ATP analogs have little effect on the conformation of the 2CARD domain

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Presentation on theme: "ATP analogs have little effect on the conformation of the 2CARD domain"— Presentation transcript:

1 Fig. 4 ATP analogs have little effect on the conformation of the 2CARD domain.
ATP analogs have little effect on the conformation of the 2CARD domain. RIG-I was mixed with RNA, followed by the indicated ATP analog. A one-way analysis of variance (ANOVA) identified an effect of ATP analog on 2CARD ejection (F5,12 = 9.362, P = ) and a Dunnett’s post hoc test identified adenosine diphosphate (ADP)–AlFx as the only sample significantly different from the +SLR14 sample that lacked ATP analog (*P = ). Error bars correspond to the SEM across replicate samples. T. H. Dickey et al. Sci Adv 2019;5:eaax3641 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

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