1. Fig. 5 LASV replication in cynomolgus monkeys.
LASV replication in cynomolgus monkeys. (A) Quantification (in FFU per milliliter) of LASV infectious particles in plasma (top), oral swabs (middle), or nasal swabs (bottom) according to the time after challenge. Individual data are presented for each animal. (B) Quantification of viral load by RT-qPCR in the plasma of animals. Individual values of each animal are presented as the number of viral RNA copies per milliliter according to the time after challenge. (C) Quantification in (FFU per milligram of tissue) of viral load in various organs, including inguinal lymph nodes (ILN), mesenteric lymph nodes (MLN), and cerebellum (Cereb.). Individual values are only presented for the three MeV controls and two MeV-Z animals because no infectious particles were detected in the organs of the other animals.
Mathieu Mateo et al., Sci Transl Med 2019;11:eaaw3163
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