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Biology of Blood and Marrow Transplantation

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Presentation on theme: "Biology of Blood and Marrow Transplantation"— Presentation transcript:

1 Biology of Blood and Marrow Transplantation
CD101, “A Perfect Storm” Against Aspergillus: In Vitro Microbiology, in Vivo Tissue Distribution, and Front-Loaded Treatment and Prophylactic Efficacy in Mouse Disseminated and Pulmonary Aspergillosis Infection Models  Voon Ong, Grayson Hough, Ken Bartizal, Abdul Sattar, Andrew Sharp, Pia Thommes  Biology of Blood and Marrow Transplantation  Volume 24, Issue 3, (March 2018) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure 1 CD101 tissue distribution and associated half-lives in various organs. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Figure 2 Survival rate of mice given prophylaxis CD101 (5, 10, or 20 mg/kg) as a single dose prior to infection in disseminated aspergillosis. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © Terms and Conditions

4 Figure 3 Survival rate of mice given prophylaxis CD101 (5, 10, or 20 mg/kg) or micafungin (2 mg/kg) as a single dose one day prior to infection in pulmonary aspergillosis. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © Terms and Conditions


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