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A “Big Data” View of the Tumor “Immunome”

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1 A “Big Data” View of the Tumor “Immunome”
Nicholas P. Restifo  Immunity  Volume 39, Issue 4, Pages (October 2013) DOI: /j.immuni Copyright © 2013 Elsevier Inc. Terms and Conditions

2 Figure 1 Immune Cells in a Tumor
Tumor masses are complex mixtures of cells that contain stromal cells, vasculature, and a wide array of immune cells. An unsupervised correlation matrix of the intra-tumor “immunome” reveals that, of the 28 cell types that were specifically analyzed, CTL, Tfh, and B cells (shown in bold) had the strongest correlations with increased disease-free survival, and these cell types were furthermore correlated with each other. Immunity  , DOI: ( /j.immuni ) Copyright © 2013 Elsevier Inc. Terms and Conditions

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