1. CD36 expression is coordinately regulated in multiple cellular compartments.
CD36 expression is coordinately regulated in multiple cellular compartments. A, left: representative bright field images (original magnification ×20) of paraffin sections from 13 low mammographic density and 14 high mammographic density tissues stained for CD36. Right: average and SEM of CD36 signal per cell. B, representative bright field images (original magnification ×5) of paraffin sections with tumor and normal adjacent tissue from 8 ER-positive tumors, 6 HER2-positive tumors, and 6 triple negative tumors stained for CD36. C, average and SEM of CD36 signal per cell for each tumor subtype. D, left: representative bright field images (original magnification ×20) of paraffin sections from 21 low mammographic density and 14 high mammographic density ER-positive IDC patients stained for CD36. Right: average and SEM of CD36 signal per cell. CA, tumor; HD, high mammographic density; LD, low mammographic density; NA, normal adjacent, TN, triple negative.
Rosa Anna DeFilippis et al. Cancer Discovery 2012;2:
©2012 by American Association for Cancer Research