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Methotrexate in acute persistent humoral rejection: an option for graft rescue  Fernando Bacal, MD, Gustavo L Sodré, MD, Daniela A Fernandes, MD, Vera.

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Presentation on theme: "Methotrexate in acute persistent humoral rejection: an option for graft rescue  Fernando Bacal, MD, Gustavo L Sodré, MD, Daniela A Fernandes, MD, Vera."— Presentation transcript:

1 Methotrexate in acute persistent humoral rejection: an option for graft rescue 
Fernando Bacal, MD, Gustavo L Sodré, MD, Daniela A Fernandes, MD, Vera D Aiello, MD, Noedir Stolf, MD, Edimar Bocchi, MD, Giovanni Bellotti, MD  The Annals of Thoracic Surgery  Volume 76, Issue 2, Pages (August 2003) DOI: /S (03)

2 Fig 1 Immunofluorescence of myocardial tissue: (A) Focal positivity for immunoglobulin G in a small vessel (white arrow) (original magnification, ×400.) (B) Granular pattern of positivity for C3 in the interstitium (original magnification, ×400.) (C) Diffuse positivity for fibrinogen in the interstitium (original magnification, ×200). The Annals of Thoracic Surgery  , DOI: ( /S (03) )

3 Fig 2 Immunosuppression therapy used to treat the rejection in a patient with persistent cellular and humoral components. (ATGAM = polyclonal antibodies; FK506 =tacrolimus; MMF =mycophenolate mofetil; OKT3 = monoclonal antibodies; Rej = rejection.) The Annals of Thoracic Surgery  , DOI: ( /S (03) )


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