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a) Arterial partial oxygen pressure (PaO2) and b) PaO2/inspired oxygen fraction (FIO2) ratio as a function of FIO2 in lungs simulated to have only alveolar ventilation/perfusion (V′A/Q′) inequality and no shunt. a) Arterial partial oxygen pressure (PaO2) and b) PaO2/inspired oxygen fraction (FIO2) ratio as a function of FIO2 in lungs simulated to have only alveolar ventilation/perfusion (V′A/Q′) inequality and no shunt. Note that with moderate to severe inequality, PaO2/FIO2 is far from constant as FIO2 changes. Peter D. Wagner Eur Respir J 2015;45: ©2015 by European Respiratory Society
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