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Miliary Brain Metastases in a Patient with ROS1-Rearranged Lung Adenocarcinoma: A Case Report  Katarzyna Dziadziuszko, MD, Edyta Szurowska, MD, PhD, Joanna.

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Presentation on theme: "Miliary Brain Metastases in a Patient with ROS1-Rearranged Lung Adenocarcinoma: A Case Report  Katarzyna Dziadziuszko, MD, Edyta Szurowska, MD, PhD, Joanna."— Presentation transcript:

1 Miliary Brain Metastases in a Patient with ROS1-Rearranged Lung Adenocarcinoma: A Case Report 
Katarzyna Dziadziuszko, MD, Edyta Szurowska, MD, PhD, Joanna Pienkowska, MD, PhD, Jacek Jassem, MD, PhD, Rafal Dziadziuszko, MD, PhD  Journal of Thoracic Oncology  Volume 9, Issue 5, Pages e34-e36 (May 2014) DOI: /JTO Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Contrast-enhanced computed tomography of the chest—mediastinal window. Neoplastic pleural thickening of the right lung. A, Initial chest computed tomography examination. B, After 4 months of crizotinib treatment. C, After 13 months of crizotinib treatment. Journal of Thoracic Oncology 2014 9, e34-e36DOI: ( /JTO ) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Miliary brain metastases developed after 6 months of commencement of crizotinib treatment—small high-intensity lesions in the cerebral cortex and basal ganglia. A, proton density–weighted MRI image. B, T2-weighted MRI image, transverse plane. MRI, magnetic resonance imaging. Journal of Thoracic Oncology 2014 9, e34-e36DOI: ( /JTO ) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 T1-weighted Gd-DTPA contrast-enhanced magnetic resonance images, sagittal plane. Miliary brain metastases developed after 6 months of commencement of crizotinib treatment (A) with partial regression after palliative brain radiotherapy and further 4 months of crizotinib treatment (B). Gd-DTPA, gadopentetate dimeglumine. Journal of Thoracic Oncology 2014 9, e34-e36DOI: ( /JTO ) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

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