2. actin

3. troponin
actin

4. tropomyosin
troponin
actin

5. tropomyosin
troponin
actin

6. myosin binding site
tropomyosin
troponin
actin

8. Ca2+
Ca2+
Ca2+
Ca2+

9. Ca2+
Ca2+
Ca2+
Ca2+
Calcium ions are released from the sarcolemma after stimulation from the T system

10. Ca2+
Ca2+
Ca2+
Ca2+

11. the calcium ions bind to the troponin and changes its shape

12. the calcium ions bind to the troponin and changes its shape

13. Ca2+
Ca2+
Ca2+
Ca2+

14. Ca2+
Ca2+
Ca2+
Ca2+

15. Ca2+
Ca2+
Ca2+
Ca2+
the troponin displaces the tropomyosin and exposes the myosin binding sites

16. Ca2+
Ca2+
Ca2+
Ca2+

17. Ca2+
Ca2+
Ca2+
Ca2+

18. Ca2+
Ca2+
Ca2+
Ca2+
the bulbous heads of the myosin attach to the binding sites on the actin filaments

19. Ca2+
Ca2+
Ca2+
Ca2+

20. Ca2+
Ca2+
Ca2+
Ca2+

21. Ca2+
Ca2+
Ca2+
Ca2+
the myosin heads change position to achieve a lower energy state and slide the actin filaments past the stationary myosin

22. Ca2+
Ca2+
Ca2+
Ca2+ A Pi A Pi A Pi

23. A Pi
Ca2+ A Pi
Ca2+ A Pi
Ca2+
Ca2+

24. ATP binds to the bulbous heads and causes it to become detachedPi
Ca2+ A Pi
Ca2+ A Pi
Ca2+
Ca2+
ATP binds to the bulbous heads and causes it to become detached

25. ATP binds to the bulbous heads and causes it to become detachedPi A Pi A Pi
Ca2+
Ca2+
Ca2+
Ca2+
ATP binds to the bulbous heads and causes it to become detached

26. hydrolysis of ATP provides the energy to “re-cock” the headsPi Pi Pi A Pi Pi Pi Pi A Pi Pi A
Ca2+
Ca2+
Ca2+
Ca2+
hydrolysis of ATP provides the energy to “re-cock” the heads

27. hydrolysis of ATP provides the energy to “re-cock” the headsPi Pi Pi A Pi Pi Pi Pi A Pi Pi A
Ca2+
Ca2+
Ca2+
Ca2+
hydrolysis of ATP provides the energy to “re-cock” the heads

28. Pi Pi Pi A Pi Pi Pi Pi A Pi Pi A
Ca2+
Ca2+
Ca2+
Ca2+

29. calcium ions are re-absorbed back into the T systemPi Pi Pi A Pi Pi Pi Pi A Pi Pi A
Ca2+
Ca2+
Ca2+
Ca2+
calcium ions are re-absorbed back into the T system

30. calcium ions are re-absorbed back into the T systemPi Pi Pi A Pi Pi Pi Pi A Pi Pi A
Ca2+
calcium ions are re-absorbed back into the T system

31. Pi Pi Pi A Pi Pi Pi Pi A Pi Pi A
Ca2+
the troponin reverts to its normal shape and the tropomyosin move back to block the myosin binding sites

32. Pi Pi Pi A Pi Pi Pi Pi A Pi Pi A
Ca2+
the troponin reverts to its normal shape and the tropomyosin move back to block the myosin binding sites

33. Pi Pi Pi A Pi Pi Pi Pi A Pi Pi A
Ca2+
the troponin reverts to its normal shape and the tropomyosin move back to block the myosin binding sites

34. phosphocreatine regenerates ATPPi Pi Pi A Pi Pi Pi Pi A Pi Pi A
Ca2+
phosphocreatine regenerates ATP

35. phosphocreatine regenerates ATPPi Pi Pi A Pi Pi Pi Pi A Pi Pi A
Ca2+
phosphocreatine regenerates ATP

36. phosphocreatine regenerates ATPPi Pi Pi A Pi Pi Pi A Pi Pi Pi A
Ca2+
phosphocreatine regenerates ATP

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