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Fig. 1 Blood nicotine levels after escalation of nicotine intake.

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Presentation on theme: "Fig. 1 Blood nicotine levels after escalation of nicotine intake."— Presentation transcript:

1 Fig. 1 Blood nicotine levels after escalation of nicotine intake.
Blood nicotine levels after escalation of nicotine intake. (A) Detailed timeline of the experiments. (B) After the last session of escalation of nicotine intake, blood nicotine levels were detected in rats that were pretreated with NicA2-J1 (2 mg/kg) (red circles) and rats that were pretreated with PBS (blue circles). Student’s t test showed no difference in blood nicotine levels between groups (t = 1.15, df = 14, P > 0.05). (C) At the termination of escalation of nicotine intake, rats that were pretreated with NicA2-J1 (10 mg/kg) exhibited nearly undetectable levels of nicotine in blood compared with the PBS-pretreated group (Student’s t test; t = 4.198, df = 14, P < 0.001). **P < 0.01. Marsida Kallupi et al. Sci Adv 2018;4:eaat4751 Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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