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B. Yuan, R. Neuman, S. H. Duan, J. L. Weber, P. Y. Kwok, N. L

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Presentation on theme: "B. Yuan, R. Neuman, S. H. Duan, J. L. Weber, P. Y. Kwok, N. L"— Presentation transcript:

1 Linkage of a Gene for Familial Hypobetalipoproteinemia to Chromosome 3p21.1-22 
B. Yuan, R. Neuman, S.H. Duan, J.L. Weber, P.Y. Kwok, N.L. Saccone, J.S. Wu, K.-Y. Liu, G. Schonfeld  The American Journal of Human Genetics  Volume 66, Issue 5, Pages (May 2000) DOI: /302904 Copyright © 2000 The American Society of Human Genetics Terms and Conditions

2 Figure 1 FHBL kindred, showing haplotypes consisting of eight markers on chromosome 3p. Solid symbols denote affected subjects. Question marks denote borderline apoβ level. The magenta-colored bars represent the region segregating with affected FHBL subjects. The American Journal of Human Genetics  , DOI: ( /302904) Copyright © 2000 The American Society of Human Genetics Terms and Conditions

3 Figure 2 Histogram of map location versus Loki score for chromosome 3p. The Loki score is the logarithm10 of the ratio of observed number of QTLs versus the expected number of QTLs in each centimorgan. The American Journal of Human Genetics  , DOI: ( /302904) Copyright © 2000 The American Society of Human Genetics Terms and Conditions


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