1. Dr Sindisiwe van Zyl sindivanzyl@gmail.com Pretoria
HIV 102
Dr Sindisiwe van Zyl
Pretoria

2. Introduction

3. MAP OF THE WORLD
© Copyright SASI Group (University of Sheffield) and Mark Newman (University of Michigan).

4. Worldwide HIV prevalence in adults aged 15 – 49 © Copyright SASI Group (University of Sheffield) and Mark Newman (University of Michigan).
Map from worldwide mapper showing country size according to HIV prevalence

5. WHAT IS HIV? retrovirus and a lentivirus – slow progress
The HUMAN IMMUNODEFICIENCY VIRUS (HIV)
retrovirus and a lentivirus – slow progress
uses the body’s own cells to make copies of itself
attacks the body’s immune system
causes AIDS – Acquired Immune Deficiency Syndrome

6. BACK TO BASICS CD4 cells – most important cells in the body “army”
HIV – targets CD4 cells, hijacks them and starts making copies of itself
VIRAL LOAD – the number of HIV copies in your body
ART antiretroviral therapy – combination of 3 or more ARVs taken to suppress the virus’ ability to make copies of itself

7. Undetectable equals Untransmittable

8. The Good News

9. Safer Conception for Couples
Serodifferent couples
One partner is HIV-negative
Other partner is HIV-positive
COUPLE CAN HAVE CONDOMLESS SEXUAL INTERCOURSE AND CONCEIVE NATURALLY

10. Safer pregnancy, labour, and delivery

11. UequalsU has changed everything!
In the past …
Women were not allowed to conceive
Women had to deliver via C-section
Women were not permitted to breastfeed
UequalsU has changed everything!

12. Safer infant feeding Mom MUST be on antiretroviral treatment
Her viral load MUST be undetectable
Mom MUST exclusively breastfeed
Six months to two years is the recommendation

13. Life expectancy on ARVs

14. More good news …

15. Newer drugs & less side-effects

16. Everyone must get tested!

17. QUESTIONS