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Designer Genes and Engineered Circuits

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Presentation on theme: "Designer Genes and Engineered Circuits"— Presentation transcript:

1 Designer Genes and Engineered Circuits
Cell  Volume 157, Issue 5, (May 2014) DOI: /j.cell Copyright © Terms and Conditions

2 The designer synthetic chromosome synIII, based on chromosome III of the budding yeast Saccharomyces cerevisiae. Image courtesy of J. Boeke. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

3 The unnatural base pair formed between the predominantly hydrophobic nucleotides d5SICS-dNaM is efficiently replicated within E. coli by the native replication machinery. Courtesy of J. Chin. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

4 The XTMS interactive platform ranks promiscuous enzymatic steps, toxicities, and yields to facilitate exploration of prospective biosynthetic pathways. Courtesy of J.-L. Faulon. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions


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