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 Cyclooxygenase (COX) independent chemopreventive mechanisms of non-steroidal anti-inflammatory drugs (NSAIDs). *Genes with a T cell factor 4 responsive.

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Presentation on theme: " Cyclooxygenase (COX) independent chemopreventive mechanisms of non-steroidal anti-inflammatory drugs (NSAIDs). *Genes with a T cell factor 4 responsive."— Presentation transcript:

1  Cyclooxygenase (COX) independent chemopreventive mechanisms of non-steroidal anti-inflammatory drugs (NSAIDs). *Genes with a T cell factor 4 responsive element in their promoter, but no reports of downregulation in response to NSAIDs. **Contradictory reports.  Cyclooxygenase (COX) independent chemopreventive mechanisms of non-steroidal anti-inflammatory drugs (NSAIDs). *Genes with a T cell factor 4 responsive element in their promoter, but no reports of downregulation in response to NSAIDs. **Contradictory reports. PPAR, peroxisome proliferator activated receptor; TGF-β, transforming growth factor β; NFκB, nuclear factor κB; VEGF, vascular endothelial growth factor; TRAIL, tumour necrosis factor related apoptosis inducing ligand. L A A Brosens et al. Gut 2005;54: Copyright © BMJ Publishing Group Ltd & British Society of Gastroenterology. All rights reserved.

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