1. Meningeal γδ T cell homeostasis is independent of inflammatory signals.
Meningeal γδ T cell homeostasis is independent of inflammatory signals. Cell suspensions were prepared from the meninges of 8- to 12-week-old C57BL/6J WT mice, bred in an SPF (A to D) versus GF (A) environment, treated or not with an antibiotic cocktail (Abx) (B), and compared with IL-1R−/−, IL-23R−/− (C), TLR2−/−, TLR4−/−, Caspase 1−/−, and NOD1−/− mice (D). Percentages of γδ T cells and IL-17 producers were analyzed by FACS as illustrated in Fig. 1. Results are representative of two to four independent experiments.
Miguel Ribeiro et al. Sci. Immunol. 2019;4:eaay5199
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