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Günaj Rakipovski et al. BTS 2018;3:

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1 Günaj Rakipovski et al. BTS 2018;3:844-857
Semaglutide Lowered TG and Prevented WD-Induced Transcriptional Changes in Liver of LDLr−/− Mice (A) WD-induced increases of liver triglycerides were dose-dependently reduced by semaglutide: $$p = , **p = , ****p < versus vehicle WD. (B) Semaglutide partially prevented WD induced increases in collagen gene expression: Benjamini-Hochberg-corrected p values: **p < 0.01; *p < 0.05 versus vehicle, WD. (C) Graphic representation of relative gene expression changes by WD and semaglutide compared to vehicle, chow. Benjamini-Hochberg-corrected p values: ****p < , ***p < 0.001, **p < 0.01; *p < 0.05 versus vehicle, WD. Uncorrected and Benjamini-Hochberg-corrected p values for Figures 5B and 5C can be found in Supplemental Table S4. TG = triglyceride. Günaj Rakipovski et al. BTS 2018;3: 2018 The Authors


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