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Genetics of Blood Pressure Regulation: Possible Paths in the Labyrinth
Luisa Foco, Cristian Pattaro American Journal of Kidney Diseases Volume 74, Issue 3, Pages (September 2019) DOI: /j.ajkd Copyright © 2019 National Kidney Foundation, Inc. Terms and Conditions
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Figure 1 (A) The MTHFR-CLCN6-NPPA-NPPB gene cluster, with indication of gene location and D′ linkage disequilibrium statistic (generated with Ensembl genome browser release 95; based on 499 single-nucleotide polymorphisms from the CEU panel of the 1000 Genomes phase 3 data set: (B) CLCN6 localization in the kidney. Immunohistochemistry shows medium signal intensity in glomerulus and strong signal intensity in distal tubules. Pattern in proximal tubules is speckled and weaker. Image credit: Human Protein Atlas version Shown is a portion of a slide of normal tissue from a male; the full image is available at (C) Kidney-related genes that are likely to be involved in blood pressure regulation. American Journal of Kidney Diseases , DOI: ( /j.ajkd ) Copyright © 2019 National Kidney Foundation, Inc. Terms and Conditions
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