1. TolA, TolB, and Pal crystal structures.
TolA, TolB, and Pal crystal structures. (A) Ribbon diagrams of TolA, TolB, and Pal. The Pseudomonas aeruginosa TolA C-terminal domain (TolAIII) (677) (PDB accession number 1LRO; 1.80 Å) is shown. The α-helix indicated by the arrow corresponds to the C-terminal 43 residues of the central domain (TolAII). (B) The Escherichia coli TolB structure (1, 72) (PDB accession number 1CRZ; 1.95 Å) showing the D1 domain and the six-bladed D2 domain (β-propeller) forming the cavity. (C) The Escherichia coli Pal lipoprotein structure (C. Abergel and A. Walburger, unpublished data) (PDB accession number 10AP; 1.93 Å). The peptidoglycan binding helix is indicated with an arrow, whereas the lateral chain of the Tyr residue of the conserved TolA binding motif (SYGK) (Fig. 8B) is shown and highlighted by the pink circle.
Eric Cascales et al. Microbiol. Mol. Biol. Rev. 2007; doi: /MMBR