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Local Control and Toxicity of Adaptive Radiotherapy Using Weekly CT Imaging: Results from the LARTIA Trial in Stage III NSCLC  Sara Ramella, MD, Michele.

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Presentation on theme: "Local Control and Toxicity of Adaptive Radiotherapy Using Weekly CT Imaging: Results from the LARTIA Trial in Stage III NSCLC  Sara Ramella, MD, Michele."— Presentation transcript:

1 Local Control and Toxicity of Adaptive Radiotherapy Using Weekly CT Imaging: Results from the LARTIA Trial in Stage III NSCLC  Sara Ramella, MD, Michele Fiore, MD, Sonia Silipigni, MD, Maria Cristina Zappa, MD, Massimo Jaus, MD, Antonio Maria Alberti, MD, Paolo Matteucci, MD, Elisabetta Molfese, MD, Patrizia Cornacchione, Carlo Greco, MD, Lucio Trodella, MD, Edy Ippolito, MD, Rolando Maria D’Angelillo, MD  Journal of Thoracic Oncology  Volume 12, Issue 7, Pages (July 2017) DOI: /j.jtho Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 (A) Tumor volume delineation at first computed tomography simulation. (B) Reduced target volume at replanning computed tomography scan. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 Marginal failures imaging: initial planning target volume (green), replanning planning target volume (red), and recurrence contour (yellow). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

4 Figure 3 Dose distribution of 95% of the prescribed dose in the initial planning, replanning, and plan sum for one of the three patients experiencing the marginal failure (yellow). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

5 Figure 4 Overall survival curve (in months) with upper and lower limits. K-M, Kaplan-Meier. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

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