1. Change in intracellular concentration of microRNA (miR)-17 in NuLi-1 bronchial epithelial cells (BECs) treated with miR-17-loaded lipid–polymer hybrid nanoparticles (LPNs).
Change in intracellular concentration of microRNA (miR)-17 in NuLi-1 bronchial epithelial cells (BECs) treated with miR-17-loaded lipid–polymer hybrid nanoparticles (LPNs). LD: low density (NuLi-1 BECs cultured to subconfluent density); HD: high density (NuLi-1 BECs cultured at confluent density). a–d) The concentration of miR-17 was measured by quantitative reverse transcription-PCR in a, c) LD and b, d) HD NuLi-1 BECs transfected with a, b) unnebulised or c, d) nebulised miR-17 LPNs at varying concentrations and compared with the concentration in BECs transfected with control LPNs. Data are presented as mean±sd. *: p≤0.05; **: p≤0.01; ***: p≤0.001, two-tailed t-test. n=4.
Sebastian Vencken et al. ERJ Open Res 2019;5:
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