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A. A. Partial 6p ideogram with a contig of BAC/P1 clones used to generate region-specific array. Each bar represents a BAC/PAC clone. B. A representative region-specific ratio profile of 6p12-p21 from case OS-204. In this experiment, tumor and normal DNA were labeled with Cy5 and Cy3, respectively. The dye reversal experiment was also done to avoid dye biases and hybridization artifacts. The mean ratios were plotted along the length of the chromosome. The clones on each chromosome are arranged (pter to qter) based on University of California at Santa Cruz mapping positions. Xin-Yan Lu et al. Mol Cancer Res 2008;6: ©2008 by American Association for Cancer Research
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