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Introduction to pathology

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1 Introduction to pathology
2019

2 course 2 credit hour Three instuctors: Dr Heyam Awad, Dr Mousa Abbadi and Dr Manar Hajeer

3 Reference Robbins basic pathology Tenth edition
Web Path Internet teaching

4 Course description lecture topic lecturer 5 Cell injury Dr manar 6
inflammation Dr mousa 3 repair 11 neoplasia Dr heyam

5 evaluation Midterm exam… .. 40 marks Final exam……50 marks
Attendance… 10 marks

6 Contact details Dr Manar hajeer
Office: third floor , clinics building, JUH

7 What is pathology The study (logos) of suffering or disease (pathos).
The study of the structural, biochemical, and functional changes in cells, tissues, and organs that are involved by disease.

8 Why pathology is important
A bridge between the basic sciences and clinical medicine. Uses molecular, microbiologic, immunologic, and morphologic techniques trying to reach a diagnosis and explanation.

9 Divisions General pathology: Cell injury, inflammation and repair, hemodynamic disorders, genetic disorders, immune system diseases, infectious disease and environmental diseases. Systemic pathology: alterations in specialized organs and tissues in diseased status.

10 Aspects of disease Epidemiological aspects Etiology/ cause:
Genetic: mutations Acquired: infectious, nutritional, chemical..

11 Aspects of disease Pathogenesis: sequence of events in the response of cells or tissues to the etiologic agent, from the initial stimulus to the ultimate expression of the disease. (mechanism).

12 Aspects of disease Molecular changes.
Morphologic changes: macroscopic versus microscopic. Clinical features including biochemical tests, physical findings, radiological findings Complications Treatment Prognosis

13 Classification of Pathology
Anatomical/ surgical pathology or histopathology: Gross examination and microscopic examination to reach a diagnosis. Clinical pathology: hematology, microbiology, immunology and biochemistry.

14 Anatomic pathology Histopathology. Cytopathology. Autopsy.
Subspecialties: neuropathology, dermatopathology, oral pathology……

15 Diagnosis in Histopathology
Biopsies: excisional and incisional. Smears: exfoliative and fine needle aspiration.

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