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Fig. 3 Ex vivo application and adhesion properties of GelCORE adhesives.
Ex vivo application and adhesion properties of GelCORE adhesives. (A) Representative slit lamp photographs from rabbit eyes sealed by GelCORE bioadhesive, and (B) retention times of GelCORE bioadhesives, formed at various cross-linking times and prepolymer concentrations, on cornea tissues. (C) Representative optical coherence tomography images after ex vivo application of GelCORE adhesives to rabbit corneas at days 1, 14, and 28 after application. (D) Schematic of ex vivo burst pressure set up, including a syringe pump, a pressure sensor, and a recording system. (E) Average burst pressure of GelCORE adhesives formed by varying photocrosslinking time, compared to a commercially available ocular sealant, ReSure (control). Data are represented as means ± SD (**P < 0.01, ***P < 0.001, and ****P < ; n ≥ 4). [Photo credit: (A) Ahmad Kheirkhah, MEE, Harvard Medical School; (D) Ehsan Shirzaei Sani, UCLA] Ehsan Shirzaei Sani et al. Sci Adv 2019;5:eaav1281 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).
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