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Published byPhoebe Strickland Modified over 5 years ago
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Removing Reprogramming Roadblocks: Mbd3 Depletion Allows Deterministic iPSC Generation
Justin Brumbaugh, Konrad Hochedlinger Cell Stem Cell Volume 13, Issue 4, Pages (October 2013) DOI: /j.stem Copyright © 2013 Elsevier Inc. Terms and Conditions
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Figure 1 Reprogramming Dynamics for Mbd3 Knockout Cells Compared to Wild-Type Cells By day 7, nearly 100% of Mbd3 knockout cells have induced pluripotency following OKSM expression, fitting a deterministic model. The dynamics of reprogramming in wild-type cells differ, suggesting a stochastic model. Cell Stem Cell , DOI: ( /j.stem ) Copyright © 2013 Elsevier Inc. Terms and Conditions
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