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Four–time point diurnal profiles of plasma glucose concentrations (A) and AUCs (B) over quintiles of HbA1c. ○, AUC1; •, AUC2; ▴, AUC2 − AUC1 (differences between the two areas). Four–time point diurnal profiles of plasma glucose concentrations (A) and AUCs (B) over quintiles of HbA1c. ○, AUC1; •, AUC2; ▴, AUC2 − AUC1 (differences between the two areas). Methods of calculation and meanings for each area are provided in the text; and results are given as the means ± SE. *Significant differences from all following upper quintiles. All P values are <0.001 after Bonferroni adjustment, except for comparisons between quintiles 1 and 2 of AUC1 (P = 0.015) or AUC2 − AUC1 (P = 0.032) and between quintiles 2 and 3 (P = 0.047) of AUC2 − AUC1. Louis Monnier et al. Dia Care 2003;26: ©2003 by American Diabetes Association
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