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Bulk Flow Redux? Cell Volume 98, Issue 2, Pages 125-127 (July 1999)
Graham Warren, Ira Mellman Cell Volume 98, Issue 2, Pages (July 1999) DOI: /S (00)
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Figure 1 Secretory Cargo in Pancreatic Acinar Cells Is Concentrated by Exclusion Amylase and chymotrypsinogen exit the ER by bulk flow in COPII vesicles budding from the transitional elements (te) of the ER. They are later concentrated in VTCs (vesiculotubular clusters) by exclusion from recycling COPI vesicles. In contrast, components that recycle, rBet1p (a presumptive v-SNARE) and the KDEL receptor, are concentrated in budding COPII vesicles and remain concentrated during the rest of the cycle. Cell , DOI: ( /S (00) )
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