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Psoriatic Arthritis
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Introduction to PsA
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Key Cell Types and Activated Pathways in Psoriatic Arthritis
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Role of IL-17 Signaling
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Pharmacologic Agents Indicated for the Treatment of PsA
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FUTURE 1 Efficacy and Safety of Secukinumab
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FUTURE 2 Efficacy and Safety of SC Secukinumab
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FUTURE 2: Efficacy of Secukinumab in Anti-TNF-Naive and Anti-TNF-IR Patients
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FUTURE 5 Improvement in Radiographic Progression
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Summary of Pooled Safety Across FUTURE 1 and FUTURE 2 Studies
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Ixekizumab for the Treatment of PsA SPIRIT-P1 Results
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SPIRIT-P2 Ixekizumab for the Treatment of PsA in TNF-IR Patients
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Frequency of AEs Across SPIRIT-P1 and SPIRIT-P2 Studies
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SPIRIT-H2H: Study Comparing Safety and Efficacy of Ixekizumab and Adalimumab in PsA
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SPIRIT-H2H Results Primary and Secondary Outcomes at Week 24
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Safety and Efficacy of Bimekizumab in Patients With PsA
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GRAPPA Treatment Scheme
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Enthesitis in PsA
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IL-17 Inhibitors in the Treatment of Enthesitis
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Dactylitis in PsA
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IL-17 Inhibitors in the Treatment of Dactylitis
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MAXIMISE Trial Managing Axial Manifestations in Patients with PsA
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Concluding Remarks
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Abbreviations
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Abbreviations (cont)
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Abbreviations (cont)
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