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Fig. 4 PPM-DD–optimized ND-drug combinations.

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Presentation on theme: "Fig. 4 PPM-DD–optimized ND-drug combinations."— Presentation transcript:

1 Fig. 4 PPM-DD–optimized ND-drug combinations.
PPM-DD–optimized ND-drug combinations. (A) A schematic model of the PPM experimental framework. Dox, doxorubicin; Bleo, bleomycin; Mtx, mitoxantrone; Pac, paclitaxel. (B) PPM-derived optimal ND-drug combinations (NDC) outperform a random sampling of NDCs in effective therapeutic windows of treatment of cancer cells compared to control cells. Reprinted (adapted) with permission from H. Wang et al., Mechanism-independent optimization of combinatorial nanodiamond and unmodified drug delivery using a phenotypically driven platform technology. ACS Nano (2015/02/17, 2015). Copyright 2014 American Chemical Society. Dean Ho et al. Sci Adv 2015;1:e Copyright © 2015, The Authors


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