1. The Challenge of Insulin Titration

3. Program Overview

4. Delays in Titration of Basal Insulin

5. Titration of Basal Insulin -- HCPs Need to Share More Information With Patients

6. The Benefits of Insulin Titration

7. The Evolution of Basal Insulins

8. Trial-Level Meta-Analyses of Nocturnal Hypoglycemia With Deg-100 and Gla-300

9. Comparing PK/PD Data

10. BRIGHT: Head-to-Head Comparison of Gla-300 and Deg-100

11. BRIGHT: Study Endpoints and Glycemic Targets

12. BRIGHT Results: Glycemic Control and Weight Changes

13. BRIGHT: Anytime (24 h) Hypoglycemia

14. BRIGHT: Nocturnal (00:00 to 06:00 h) Hypoglycemia

15. RCT Data: Implications for Clinical Practice

16. The Role of RCTs and RWE

17. The Role of RCTs and RWE (cont)

18. Patient-Led Titration of Basal Insulin: TAKE CONTROL

19. Patient-Led Titration of Basal Insulin: TAKE CONTROL (cont)

20. Implications of RCTs and TAKE CONTROL for Basal Insulin Titration

21. Other RWE for Second-Generation Basal Insulins

22. Basal Insulin Titration in Clinical Practice

23. How Clinicians Can Help Patients Take Control of Titration

24. Conclusions

25. Abbreviations

26. Abbreviations (cont)