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Fig. 1 The combination of PCET and an RNR class I reaction enables heteroarene C─H alkylation using ketones and aldehydes as alkyl radical equivalents.

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Presentation on theme: "Fig. 1 The combination of PCET and an RNR class I reaction enables heteroarene C─H alkylation using ketones and aldehydes as alkyl radical equivalents."— Presentation transcript:

1 Fig. 1 The combination of PCET and an RNR class I reaction enables heteroarene C─H alkylation using ketones and aldehydes as alkyl radical equivalents. The combination of PCET and an RNR class I reaction enables heteroarene C─H alkylation using ketones and aldehydes as alkyl radical equivalents. (A) The polarity of the C═O bond. HAT, hydrogen atom transfer. (B) A new catalyst system for reductive PCET. (C) The RNR class I reaction. (D) The method reported herein. Jianyang Dong et al. Sci Adv 2019;5:eaax9955 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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