1. Analysis of pharmacodynamic interaction of sevoflurane and propofol on bispectral index during general anaesthesia using a response surface model 
J.C. Diz, R Del Río, A Lamas, M Mendoza, M Durán, L.M. Ferreira 
British Journal of Anaesthesia 
Volume 104, Issue 6, Pages (June 2010)
DOI: /bja/aeq081
Copyright © 2010 The Author(s) Terms and Conditions

2. Fig 1
e′SEVO (%), CePROPO (µg ml−1), and BIS values in the six study periods. The bars represent the mean (sd).
British Journal of Anaesthesia  , DOI: ( /bja/aeq081)
Copyright © 2010 The Author(s) Terms and Conditions

3. Fig 2
Topographic view of the actual values of e′SEVO (%) and CePROPO (µg ml−1) used in the study with their BIS values, overlaid on the isoboles that produce target BIS values of 40, 50, and 60.
British Journal of Anaesthesia  , DOI: ( /bja/aeq081)
Copyright © 2010 The Author(s) Terms and Conditions

4. Fig 3
Relationship of e′SEVO (%) and CePROPO (µg ml−1) with predicted value of BIS according to the parameters estimated in the response surface model.
British Journal of Anaesthesia  , DOI: ( /bja/aeq081)
Copyright © 2010 The Author(s) Terms and Conditions

5. Fig 4
Graphs showing the relationship between (a) U50(θ), (b) Emax(θ), and (c) γ(θ) at different normalized concentrations of sevoflurane and propofol expressed by θ.
British Journal of Anaesthesia  , DOI: ( /bja/aeq081)
Copyright © 2010 The Author(s) Terms and Conditions

6. Fig 5
Standardized weighted residuals of the difference between measured and predicted BIS values for different ratios θ of sevoflurane and propofol.
British Journal of Anaesthesia  , DOI: ( /bja/aeq081)
Copyright © 2010 The Author(s) Terms and Conditions