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You Don't Know JAK in IBD
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Epidemiology of IBD
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Burden of Disease
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Factors Contributing to Pathogenesis of IBD
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CD and UC Are Progressive
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CD and UC Are Progressive (cont)
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Immunopathogenesis of IBD
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Goals of IBD Therapy
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Treat to Target
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FDA-Approved Therapies for IBD
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Limitations of Current IBD Treatments
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New and Emerging Treatments in IBD
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Tofacitinib
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Tofacitinib in Adults With UC OCTAVE 1 and 2 Studies
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Tofacitinib in CD
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Investigational JAK Inhibitors in IBD
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Filgotinib in Moderate to Severe CD FITZROY Study Results
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Upadacitinib in Moderate to Severe CD Celest Study Results
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IL-12/-23 Antagonists
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Selective Adhesion Molecule Inhibitors
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S1P Receptor Modulators
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S1P Receptor Modulators (cont)
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Other Emerging Therapies in IBD
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Concluding Remarks
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Abbreviations
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Abbreviations (cont)
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