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Fig. 3 Evaluation of PTMAO immunogenicity.
Evaluation of PTMAO immunogenicity. C57BL/6J mice were subcutaneously injected with either PEG-KLH or PTMAO-KLH (n = 5) for five doses (one dose per week). SC, subcutaneous. Mice blood was collected on day 7, 14, 21, 28, and 35 (A). The titer of polymer-specific IgM (B) and IgG (C) in mice sera was detected with ELISA tests. All statistical analyses were performed using Student’s t test. NS, no significant difference. ***P < Bowen Li et al. Sci Adv 2019;5:eaaw9562 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).
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