Presentation is loading. Please wait.

Presentation is loading. Please wait.

Fig. 4 Orthosteric ligand-binding pocket in CysLT1R.

Published byἈγαυή Βαμβακάς Modified over 5 years ago

Similar presentations

Presentation on theme: "Fig. 4 Orthosteric ligand-binding pocket in CysLT1R."— Presentation transcript:

1 Fig. 4 Orthosteric ligand-binding pocket in CysLT1R.
Orthosteric ligand-binding pocket in CysLT1R. (A and D) Details of ligand-receptor interactions for pranlukast (A) and zafirlukast (D). (B and E) Pocket shapes for pranlukast (B) and zafirlukast (E). (C and F) Pocket entrance for pranlukast, closed “gate” (C), and zafirlukast, open “gate” (F). (G and H) 2D representations of receptor-ligand interactions for pranlukast (G) and zafirlukast (H). Water molecules are shown as red spheres in (A). Residues engaged in the same type of interactions with both zafirlukast and pranlukast are colored in light green, and those engaged in different types are colored in orange (G and H). The membrane boundary is shown as a dashed line in (B, C, E, and F). Aleksandra Luginina et al. Sci Adv 2019;5:eaax2518 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

Download ppt "Fig. 4 Orthosteric ligand-binding pocket in CysLT1R."

Similar presentations

Fig. 5 Correlation of RNA expression and protein abundance.

Fig. 5 Correlation of RNA expression and protein abundance.
Fig. 2 Transport properties of a BP transistor at low temperature.

Fig. 2 Transport properties of a BP transistor at low temperature.
Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,

Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,
Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)

Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)
Fig. 3 Oil, gas, and FP water variations with time.

Fig. 3 Oil, gas, and FP water variations with time.
Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.

Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.
Fig. 1 Evolution of magnetic field lines around a foreshock bubble in the GSE-XY plane (z = 0): Results of a hybrid simulation. Evolution of magnetic field.

Fig. 1 Evolution of magnetic field lines around a foreshock bubble in the GSE-XY plane (z = 0): Results of a hybrid simulation. Evolution of magnetic field.
Fig. 1 Map of water stress and shale plays.

Fig. 1 Map of water stress and shale plays.
Fig. 1 Examples of experimental stimuli and behavioral performance.

Fig. 1 Examples of experimental stimuli and behavioral performance.
Fig. 3 Electron PSD in various regions.

Fig. 3 Electron PSD in various regions.
Fig. 2 Some examples of weekly forecasts (the number of the forecasts are reported on Table 1). Some examples of weekly forecasts (the number of the forecasts.

Fig. 2 Some examples of weekly forecasts (the number of the forecasts are reported on Table 1). Some examples of weekly forecasts (the number of the forecasts.
Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.

Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.
HT synthesis of boronic acids using the building block approach

HT synthesis of boronic acids using the building block approach
Fig. 6 Comparison of properties of water models.

Fig. 6 Comparison of properties of water models.
Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.

Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.
Fig. 2 Ferroelectric domains resolved in WTe2 single crystals.

Fig. 2 Ferroelectric domains resolved in WTe2 single crystals.
Fig. 2 Stratigraphic profile of the Area 15 excavation block showing the diagnostic cultural materials and components alongside the stratigraphic sequence.

Fig. 2 Stratigraphic profile of the Area 15 excavation block showing the diagnostic cultural materials and components alongside the stratigraphic sequence.
Fig. 3 Rotation experiment, setup.

Fig. 3 Rotation experiment, setup.
Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.

Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.
Fig. 1 Reference-fixing experiment, setup.

Fig. 1 Reference-fixing experiment, setup.

Similar presentations

Ads by Google