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Mother's Milk and Intrinsic Immunity
Marc-André Langlois Cell Host & Microbe Volume 8, Issue 6, Pages (December 2010) DOI: /j.chom Copyright © 2010 Elsevier Inc. Terms and Conditions
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Figure 1 APOBEC3 Restricts MMTV Vertical Transmission and Spread within the Host (A) APOBEC3 restricts vertical transmission. Foster-nurtured APOBEC3-deficient mice (−/−) displayed a high incidence of MMTV-related mammary tumors. Milk produced by infected wild-type (+/+) mice contained fewer and less infectious MMTV particles. (B) APOBEC3 restricts the spread of MMTV infection. APOBEC3-deficient and wild-type mice were irradiated and reconstituted with wild-type bone marrow prior to infection with MMTV. The tumor incidence was similar in both mice. Cell Host & Microbe 2010 8, DOI: ( /j.chom ) Copyright © 2010 Elsevier Inc. Terms and Conditions
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