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(A and B) Low-grade serrated dysplasia, on the other hand, is characterised by ovoid enlarged nuclei, vesicular dispersed chromatin and occasional mitoses. (A and B) Low-grade serrated dysplasia, on the other hand, is characterised by ovoid enlarged nuclei, vesicular dispersed chromatin and occasional mitoses. (C) As part of the serrated dysplastic process is a dysmaturation phenomenon with uneven distribution of goblet cells within crypts and the presence of so-called ‘inverted’ goblet cells (arrow). (D) So-called ‘floating’ goblet cells are seen irregularly distributed within the lining and not luminally oriented as in normal mature mucosa (arrows). Runjan Chetty J Clin Pathol 2016;69:6-11 Copyright © by the BMJ Publishing Group Ltd & Association of Clinical Pathologists. All rights reserved.
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