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Human cytomegalovirus vaccine development strategies.
Human cytomegalovirus vaccine development strategies. Various vaccine strategies have been developed, including live attenuated, recombinant viral proteins, dense bodies, vector vaccine subunit, or synthetic peptide epitopes. These formulations have been extensively tested using different animal models and have shown promising immunogenicity and protective efficacy (21, 30, 100, ). Some of these strategies have already progressed to clinical trials with humans (1, 3, 18, 67, 75, 88, 104, 118, 176, 182, 191, 198, 199). Tania Crough, and Rajiv Khanna Clin. Microbiol. Rev. 2009; doi: /CMR
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