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Genetic events contributing to the evolution of Shigella spp

Published byΑμύντα Ανδρεάδης Modified over 5 years ago

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Presentation on theme: "Genetic events contributing to the evolution of Shigella spp"— Presentation transcript:

1 Genetic events contributing to the evolution of Shigella spp
Genetic events contributing to the evolution of Shigella spp. from nonpathogenic E. coli ancestors. Genetic events contributing to the evolution of Shigella spp. from nonpathogenic E. coli ancestors. Shigella spp. evolved from nonpathogenic E. coli through the acquisition of a large virulence plasmid and chromosomal pathogenicity islands as well as through the loss of genetic loci, which are not functional intracellularly or impede virulence. SRL, Shigella resistance locus. (Modified from reference 191 with permission from Macmillan Publishers Ltd.)‏ Gunnar N. Schroeder, and Hubert Hilbi Clin. Microbiol. Rev. 2008; doi: /CMR

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