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Blood Typing ABO
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NOTE: A and B are codominant
ABO Blood Group Three alleles A, B, O or IA, IB, i Phenotypes of Blood types: A B AB O NOTE: A and B are codominant Blood Typing You Tube (ABO and Rh) 13:15 – nice donut analogy
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Blood Donating Diagram
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Blood Typing Punnetts
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"What are the blood types that the father would have of a mother of blood type A for a son to have type B blood?" B or O A, B, AB or O AB or B A or B A, B, or AB
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"What are the blood types that the fathers would have of a mother of blood type A for a son to have type B blood?" B or O A, B, AB or O AB or B A or B A, B, or AB
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Drop of Blood Red blood cells have antigens Plasma has antibodies
Don’t mix same letter antigens with antibodies
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Antigens (glycoproteins)-identify the blood type
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Antigens on RBC antigens antibodies
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Antigens on surface Rh A
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B antigens on surface Rh B
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Both A and B antigens on surface
Rh
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Hey, if Type O has A and B antibodies…
Why can you give it to every other type of blood? The donated blood only has a very small amount of antibodies. It is more important what kind of immune antibody response it will cause to happen. It will not cause any antibodies to be formed in the blood it is being given to.
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Alleles and antibodies
Anti-A Anti-B A B AB none None Clump
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Agglutination (clumping) antibodies join forming a big complex
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Official Blood Test Card
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Blood Typing Simulation
A sera is colored blue B sera is colored yellow Rh sera is colorless
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ABO Blood Type ABO Blood Typing
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Type A+ A Rh B
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Type B+ A Rh B
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Type AB+ A Rh B
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Type O- A Rh B
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Rh+ and Rh- dominant Rh positive gene (+) produces the Rh antigen
recessive Rh negative gene (-) does not produce an antigen
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Rh Factor Genotypes Rh+/Rh+ Rh+ Rh+/Rh- Rh-/Rh- = Rh-
Rh factor named from Rhesus monkeys that were used to do blood tests
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O positive and negative blood
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Rh Punnett Squares D= + d = -
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Rh Punnett Squares
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Rh + or - ? Anti-Rh antibodies
. HINT: which blood has the Rh antigens on it?
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Rh + or - ? Anti-Rh antibodies
Rhesus isoimmunisation, Rh (D) disease Anti-Rh antibodies . HINT: which blood has the Rh antigens on it? Rh+
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Best Blood for donation centers
Universal donor = O Negative Universal recipient AB Positive.
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Percentages in U.S. O Positive 38.4% A Positive 32.3% B Positive 09.4%
O Negative 07.7% A Negative 06.5% AB Positive 03.2% B Negative 01.7% AB Negative 00.7%
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