1. Psoriasis Psoriatic Arthritis Cellulitis
Pathophysiology
Psoriasis
Psoriatic Arthritis
Cellulitis

2. Psoriasis
Psoriatic Arthritis
Cellulitis

3. aps

4. nerps

5. Psoriasis
Psoriatic Arthritis
Cellulitis

6. aps

7. Psoriatic arthritis

8. An inflammatory arthritis that occurs in a patient with psoriasis.
Harrison’s Internal Medicine 17th edition
A form of arthritis that occurs in patients with psoriasis with the hallmarks of an "inflammatory" arthritis, including joint pain, erythema, and swelling, often with prominent stiffness.
Mease, P., Menter, A. (2005) , Psoriatic Arthritis: Understanding Its Pathophysiology and Improving Its Diagnosis and Management. Retrieved from:

9. Clinical Features Unique to Psoriatic Arthritis: DIP joint involvement
Nail changes
Dactylitis
Enthesitis
Spondylitis Lytic and periarticular new bone formation x-ray features
Iritis or Uveatis
Mease, P., Menter, A. (2005) , Psoriatic Arthritis: Understanding Its Pathophysiology and Improving Its Diagnosis and Management. Retrieved from:

10. Clinical Features Patterns of Arthropathy Arthritis of DIP joints
Asymmetric oligoarthritis
Symmetric polyarthritis
Axial involvement
Arthritis Mutilans

11. Psoriatic Arthritis Distal Interphalangeal joint arthritis
Occurs in 15 % of cases
Nail changes also seen
Harrison’s Internal Medicine 17th edition

12. Psoriatic Arthritis Asymmetric Oligoarthritis
Involves the knee or any large joint with a few small joints in the fingers and toes
Metarsophalangeal
Proximal interphalengeal
Distal interphalengeal
Dactylis
Sausage shaped digits due to inflammation of the flexor tendons and synovium and pitting edema of the distal extremities may be observed
Harrison’s Internal Medicine 17th edition

13. Psoriatic Arthritis Symmetric polyarthritis
Affects the Hands, wrists, knees, and feet symmetrically
Proximal interphalangeal joints
Metacarpophalangeal joints
Peripheral joints are less tender compared to RA
Harrison’s Internal Medicine 17th edition

14. Psoriatic Arthritis Axial Arthropathy Spine and sacroiliac joints
Harrison’s Internal Medicine 17th edition

15. Psoriatic Arthritis Arthritis mutilans
Widespread shortening or telescoping of digits due to osteolysis of the phalanges and metacarpals
coexisting with ankylosis and contractures in other digits
opera-glass deformity or pencil-in-cup radiographic findings
Fever
Harrison’s Internal Medicine 17th edition

16. Nail Changes Pitting Horizontal ridging Onycholysis
Discoloration of nail margins
Dystrophic hyperkeratosis
Nail pitting
Onycholysis
Onychodystrophy
Harrison’s Internal Medicine 17th edition

17. Dactylitis
Involvement of the distal and proximal interphalangeal joints, together with tendon sheath involvement, may give the digit a sausage shape
Harrison’s Internal Medicine 17th edition

18. Enthesitis
Inflammation at the sites of ligamentous and tendinous insertions
Emedicine Retrieved from:

19. Immunocompromised due to meds Auspitz sign – break in skin integrity
Psoriasis
Psoriatic Arthritis
Cellulitis
Risk Factors:
Immunocompromised due to meds
Auspitz sign – break in skin integrity

20. Psoriasis
Immunocompromised patient due to medications
Auspitz sign
Break in the skin integrity
Bacteria gains access to the epidermis
Acute inflammation of the dermis and subcutaneous tissue
Indigenous flora colonizing the skin
Staphylococcus aureus
Streptococcus pyogenes
Exogenous bacteria
Cellulitis
Harrison’s Principles of Internal Medicine 17th ed.

21. Cellulitis At the involved site Fever and chills Malaise
Localized pain
Erythema
Swelling
Warmth
Borders are not sharply demarcated
Fever and chills
Malaise
Harrison’s Principles of Internal Medicine 17th ed.