1. SAVING LIVES AND CREATING IMPACT EU investment in poverty-related neglected diseases

2. Levels of funding Nature of funding Health impact Economic impact Research capacity Jobs created Leveraged investment Scientific excellence Industrial competitiveness Health in the EU Integration Growth and competitiveness in the EU Health and prosperity in developing countries EU Investment in PRND R&D 2 How have developing countries benefitted? 3 What is the return on investment for Europe? = + 1 What has the EU invested in PRND R&D?

3. The EU invests €341 million a year in PRND R&D 15% OF ALL FUNDING FOR PRND R&D 1 What has the EU invested in PRND R&D?

4. Top Funders €93 m 1 st EC €87 m 2 nd UK €53 m 3 rd France 1 What has the EU invested in PRND R&D?

5. Sweden 0.0054% UK 0.0049% Ireland 0.0047% EU 0.0024% Finland 0.0004% Denmark 0.0042% France 0.0013% Luxembourg 0.0032% Belgium 0.0016% Netherlands 0.0035% Germany 0.0007% Italy 0.0002% Spain 0.0013% Member State Funding by GDP USA 0.01% Brazil 0.0017% India 0.0017% 1 What has the EU invested in PRND R&D?

6. MDG 1 Eradicate Extreme Poverty and Hunger MDG 2 Achieve Universal Primary Education MDG 3 Promote Gender Equality and Empower Women MDG 4 Reduce Child Mortality MDG 5 Improve Maternal Health MDG 6 Combat HIV/AIDS, Malaria and other diseases MDG 7 Ensure Environmental Sustainability MDG 8 A Global Partnership for Development Pharmaceutic al Innovation 2 How have developing countries benefitted?

7. EU investment has contributed to the creation of 43 new PRND products 2 How have developing countries benefitted?

8. MALARI A KEY PHARMACEUTICAL INNOVATIONS 1.COARTE M 2.ASAQ 3.EUARTES IM 2 How have developing countries benefitted? INFECTS 216+ MILLION PEOPLE KILLS AROUND 655,000 PEOPLE Image Credit: Anne Heslop Photography

9. 359 products in development 43% involving European developers FOR VACCINES ALONE, THERE ARE PROMISING CANDIDATES FOR BURULI ULCER, TUBERCULOSIS AND SCHISTOSOMIASIS 2 How have developing countries benefitted?

10. Medical Research Council, Gambia Medical Research Unit – Albert Schweitzer Hospital, Gabon Ifakara Health Institute, Tanzania Manhiça Health Research Centre, Mozambique International Centre for Diarrhoeal Disease Research, Bangladesh 2 How have developing countries benefitted? Key Developing Country Research Institutions in Africa & Asia

11. EU investment created more than 13,000 jobs 3 What is the return on investment for Europe?

12. Two-thirds of Europe’s PRND R&D funding is invested back into Europe 3 What is the return on investment for Europe?

13. €1 €1.53€1.98 €2.05 Industry €0.53 Philanthropy €0.45 Other gov’ts€0.07 3 What is the return on investment for Europe?

14. Top European PRND Research Institutes Institut Pasteur Liverpool School of Tropical Medicine London School of Hygiene & Tropical Medicine Statens Serum Institute Institute of Tropical Medicine Swiss Tropical Institue of Public Health Karolinska Institute Royal Tropical Institute Barcelona Centre for International Health Research Heidelberg University University of Tübingen Bernhard Nocht Institute for Tropical Medicine 3 What is the return on investment for Europe?

15. The European pharmaceutical industry invested six times more than the U.S. industry relative to annual revenues 6x6x 3 What is the return on investment for Europe?

16. Opportunity: Horizon 2020 Increased PRND R&D investment under Horizon 2020 will benefit both developing countries and Europe Opportunity: Horizon 2020

17. Collaboration & partnerships Building Capacity in Developing Countries Quality Research Integrating Industry = + + ++ Opportunity: Horizon 2020 EU Investment in PRND R&D = Growth and competitiveness in the EU Health and prosperity in developing countries +

18. Recommendations 1 Increase investments in PRND R&D including an increased commitment from the EC under Horizon 2020 Recommendations

19. 2 Retain and foster the distinctive benefits of its approach to funding PRND R&D Recommendations

20. 3 Improve specific aspects of its investment in PRND R&D, to ensure greater efficiency, impact and value Recommendations

21. Thank you