1. ANTIGEN-ANTIBODY INTERACTION LECTURER: DAVID

2. OBJECTIVES

3. INNATE VERSUS ADAPTIVE RESPONSE INNATEADAPTIVE

4. ANTIBODY!

5. ANTIBODY STRUCTURE

6. WHAT IS AN ANTIBODY??

7. BUT WHAT IS AN ANTIGEN???

8. SUMMARY

9. ANTIBODY FUNCTIONS

10. NEUTRALIZATION

11. OPSONIZATION

12. COMPLEMENT

13. AGGLUTINATION

15. ABO BLOOD GROUPS

16. THERE ARE LOTS OF TYPES OF ANTIBODIES

17. IgG

18. IgA

19. IgM

20. IgE

21. IgD

22. OBJECTIVES

23. QUESTION Which immunoglobulin can cross the placenta?

24. ANSWER IgG

25. QUESTION If you mix a person with type A blood and anti-A antibodies, will agglutination occur?

26. ANSWER Yes

27. QUESTION What is the difference between neutralization and opsonization?

28. ANSWER Neutralization – antibody binds a toxin and makes it harmless Opsonization – antibody binds an antigen and targets it for phagocytosis

29. LAB TODAY Today you will be simulating the Ouchterlony test. This test is performed on an agar plate Antigen and antibodies are placed in well and allowed to diffuse. If an interaction occurs between an antibody/antigen, then a white line appears.