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Ag Distributors, LLC Germ Control 24 Silver Formula Commercial Blend PO Box 287 Mukwonago, WI 53149 Phone: 414.430.2539 / Fax: 714.384.7526 www.agdistributorsllc.comwww.agdistributorsllc.com / sales@agdistributorsllc.comsales@agdistributorsllc.com
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In North America 44,000 people die annually of infections from drug-resistant germs. Listeria: 2,500 infections and 500 deaths annually. Salmonella: 40,000 infections and 600 deaths annually. E. coli: 73 infections and 61 deaths annually. 31% of all patients leaving the hospital have to go back and be treated for infections that they got while at the hospital (Tommy Thompson, former Secretary of Health and Human Services). In The Hospital 2,000,000 PATIENTS in the U.S. become infected each year while hospitalized. 100,000 patients a year die as a result of their infection (population of Green Bay). More than 70% of the bacteria causing these infections are resistant to antibiotics. Cost of hospital acquired infections: $29 Billion in the U.S. each year! The Facts: 1
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The Solution! Silver Dihydrogen Citrate – Ionic Silver Technology Old … Silver has been used for thousands of years, as far back as ancient Egypt, Greece and Rome where the primary application was to disinfect water by placing silver bars in the aqua ducts. New … Silver Dihydrogen Citrate is revolutionary technology…stabilized Ionic Silver in a tasteless, odorless and colorless non-toxic liquid with superb efficacy against bacteria, fungi and viruses. 2
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Silver’s Evolution Solid Silver - Used for thousands of years to inhibit bacteria - Primary for water and wound care Colloidal Silver - Smaller and more efficacious than Bar Silver - Abused by MLM Marketers during the 80’s & early 90’s - FDA – aggressive position against MLM’s Ionic Silver – Electrically Generated (Non-Stabilized) - Smaller and more efficacious than Colloidal Silver - Requires electrical current to maintain stability - Used in pools and other re-circulating systems Silver Dihydrogen Citrate – Germ Control 24 Silver Formula - Completely Stabilized - Completely Stabilized - The efficacy of Electrically Generated Ionic Silver without the cord - The efficacy of Electrically Generated Ionic Silver without the cord 3
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5 SDC can also act on an organism’s outer membrane. Silver ions are highly attracted to sulfur-containing thiol groups found in metabolic and structural proteins bound to the membrane surface. SDC targets these critical proteins and destroys their structure. This disruption of the organisms membrane function and integrity, lyses the membrane and the organism dies. SDC Dual Modes of Action Unlike traditional antimicrobials, bacteria are actually attracted to SDC because they recognize citric acid as a food source. This “Trojan Horse” attack allows SDC to easily enter the microorganism through membrane transport proteins. Once inside the organism, SDC binds to DNA and intracellular proteins causing irreversible damage to the DNA and protein structure. Metabolic and reproductive functions halt, and the organism dies. Silver dihydrogen citrate’s rapid and broad spectrum efficacy is largely attributed to its dual mechanisms of action and unique characteristics. These two mechanisms, alone or in combination, make SDC a powerful antimicrobial while mitigating microbial resistance. Regardless of the type of kill mechanism, surplus SDC provides residual protection.
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Benefits of Germ Control 24 Silver Formula 24 Hour Residual Antimicrobial Activity Odorless Colorless Safe, Non-Toxic Non-Corrosive to Metals Broad Spectrum of Efficacy Does Not Induce Bacterial Resistance 6
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Germ Control 24 Silver Formula Mechanism of Action – Dry Surface 7 The “Silver Bullet” to this Ongoing Dilemma Biocidial Activity Even at incidental levels, microbes are transported by means that have enough inherent moisture to react with Germ Control 24 Silver Formula treated surface.
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Germ Control 24 Silver Formula Intellectual Property Patents and Worldwide Marketing Rights Four Issued Patents #6,197,814 (March, 2001) #6,583,176 (June, 2003) #6,890,953 (May, 2005) #7,261,905 (August, 2007) 70 + countries received or in process Multiple application/use patents filed 8
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AOAC Carrier Confirmation Standard Indicator Organisms Goal Verify Germ Control 24 Silver Formula disinfectant activity against standard indicator organisms. Germ Control 24 Silver Formula was tested against: Staphylococcus aureus ATCC #6538, Pseudomonas aeruginosa ATCC# 15442 Salmonella choleraesius ATCC# 10708 In the presence of 5% organic load AOAC Protocol/ GLP conditions Final Result Germ Control 24 Silver Formula demonstrated complete disinfection in 30 seconds. 9
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Goal To verify the disinfectant efficacy of Germ Control 24 Silver Formula against additional organisms. Germ Control 24 Silver Formula was tested against the following organisms Staphylococcus aureus (MRSA) ATCC# 700698 – Methicillin Resistant Enterococcus faecium (VRE) ATCC# 700221 – Vancomycin Resistant Listeria monocytogenes ATCC# 19111 Escherichia coli OH157 ATCC# 43888 Testing performed under worst case conditions (5% organic load) AOAC Protocol/ GLP conditions Final Result MRSA – 99.9999% kill in 2 minutes VRE – 99.9999% kill in 2 minutes Listeria – 99.9999% kill in 30 seconds E. coli – 99.9999% kill in 2 minutes AOAC Carrier Confirmation Additional Organisms 10
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Goal To verify the fungicidal activity of Germ Control 24 Silver Formula Product was tested against the following organisms Trichophyton mentagrophytes ATCC# 9533 – (Athlete's Foot Fungus) AOAC Protocol/ GLP conditions Fungicidal AOAC Testing Final Result Fungicidal in less than 10 minutes. According to AOAC Guidelines, data supports a 10 minute kill time label claim. 11
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Goal To determine the residual kill activity of Germ Control 24 Silver Formula after application to a surface. Germ Control 24 Silver Formula was tested against the following organisms Staphylococcus aureus ATCC #6538 Pseudomonas aeruginosa ATCC #15442 Salmonella choleraesius ATCC #10708 The surface was tested after 1, 6 and 24 hours. AOAC Protocol/ GLP conditions Exclusive Residual Activity Final Result After 24 hours … Germ Control 24 Silver Formula still produces a bacterial kill in 2 minutes or less. 12
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HIV I Virus Goal: To verify the virucidal efficacy of Germ Control 24 Silver Formula against HIV Product was tested against HIV1 AOAC Protocol/ GLP conditions Final Result: Complete inactivation in 30 seconds Influenza A Virus Goal: To verify the virucidal efficacy of Germ Control 24 Silver Formula against Influenza A Virus Product was tested against Influenza A ATCC VR-544 AOAC Protocol/GLP conditions Final Result: Complete inactivation in 10 minutes Viruses 13
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Goal:To verify the virucidal efficacy of Germ Control24 Silver Formula against specific viruses. Goal: To verify the virucidal efficacy of Germ Control24 Silver Formula against specific viruses. Product was tested against the following viruses - Polio Type 2 - Rhino Virus - Herpes Simplex Type 1 AOAC Protocol/ GLP conditions Final Result Complete inactivationin 10 minutes Rhino Virus – Complete inactivation in 10 minutes Complete inactivationin 1 minute Herpes Simplex Type 1 – Complete inactivation in 1 minute Complete Inactivationin 10 minutes Polio Type 2 – Complete Inactivation in 10 minutes Polio, Rhino & Herpes Simplex 14
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P. Acne Kill Time Study Goal: To assess the efficacy of Axen against P. acnes. Axen was tested at 30 ppm against Propionibacterium acnes ATCC# 6921 at six time points( 15, 30, 45, 60, 75 and 90 seconds). AOAC Protocol/ GLP conditions Final Result: 99.9998 % reduction in 15 seconds 15
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Study Residual Virucidal Efficacy of a Disinfectant for Use on Inanimate Environmental Surfaces Utilizing Feline Calicivirus as a Surrogate Virus for Norovirus. This study has been performed by ATS Labs under Good Laboratory Practice regulations (40 CFR Part 160) and in accordance to standard operating procedures and a standard protocol. New: September 2007 16
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17 Complete test report is available for review upon request
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Unparalleled Efficacy Consumer Hard Surface Disinfectant …… What Competition? 18
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Pure Bioscience Receives EPA Registration of Expanded Efficacy Claims for its SDC Based Disinfectants San Diego, Calif., November 7 th, 2007 – Pure Bioscience. Pure Bioscience announces new EPA Registered Kill Claims for the Following: Avian Influenza A (Bird Flu) Human Corona Virus (SARS surrogate) Feline Calicivirus (Norovirus) Rotavirus Campylobacter jejuni Acinetobacter Community Associated MRSA (CA-MRSA) Community Associated PVL Positive MRSA (CA-MRSA, PVL Positive) To read the full story on these amazing new kill claims, please point your browser to: http://www.purebio.com/about/news New: November 2007
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Safety EPA Category IV (Use Solution) Non-Toxic Non-Corrosive to Metals No Irritating Fumes 19
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SilverDihydrogenCitrate (SDC) Pharma PersonalCare Preservative Household Food / Water Industrial SDC Platform Technology 20
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Potential Product Applications 21 EPA Applications Environmental Drinking water purification Swimming pool treatment Disinfections Food Processing Vet Spray – Parvo Medical/Dental Inst. Pre-Clean Carpets Hard Surface Disinfectants Wipes/Towelettes HS Mops and Cleaning Aids Industrial Mold Remediation Cooling Towers/Bio-film control Industrial Fluid Treatment Bio-Terrorism Assistance Mass Transit Disinfection Public Decon Stations FDA Applications Pharmaceutical Acne care Athletes foot control Nail Fungus control Wound/Burn care Diabetic Ulcer Care Diaper Dermatitis Toothpaste/ Mouthwash Cold/Canker Sores Intravaginal/Perineal Disinfections Bandages/Dressings Fruit and Vegetable Wash Teat wash Hand soap Hand Sanitizer Wipes/Towelettes Food Processing
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Formulated for use where bacteria, viral and fungal pathogens are prevalent and at risk of infecting our communities. Primary Market Focus Hospitals, Surgery Centers, Clinics, etc. Health Spas, Gyms, Health Clubs, etc. Prison Systems/ Correctional Institutions Restaurants Schools & Universities, R&D Firms Athletic Teams & Facilities Nursing Homes / Long Term Care Day Care Centers, Dental Offices, Veterinary Clinics Germ Control 24 Silver Formula 22 ALWAYS CHECK OUR WEBSITE FOR THE MOST UPDATED PRICES AND SPECIALS. Unit Size / PricePackaging / PricePallet Size / PriceCase 32 oz / $12 x 1 Case / $36 Cases / $Includes Shipping to Continental U.S. 1 Gallon / $4 x 1 Case / $36 Cases / $Includes Shipping to Continental U.S. 55 Gallon Drum1 x 55 Gal4 DrumsContact us for Pricing 275 Gallon Tote1 x 275 Gal1 ToteContact Us for Pricing
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Material Safety Data Sheet Germ Control 24 Silver Formula - RTU 23
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This presentation includes statements that may constitute "forward-looking" statements, usually containing the words "believe", "estimate", "project", "expect" or similar expressions. These statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements inherently involve risks and uncertainties that could cause actual results to differ materially from the forward-looking statements. Factors that would cause or contribute to such differences include, but are not limited to, acceptance of the Company's current and future products and services in the marketplace, the ability of the Company to develop effective new products and receive regulatory approvals of such products, competitive factors, dependence upon third-party vendors, and other risks detailed in the Company's periodic report filings with the Securities and Exchange Commission. By making these forward- looking statements, the Company undertakes no obligation to update these statements for revisions or changes after the date of this presentation. For more information, please contact: Ag Distributors, LLC Office – 414.430.2539 Fax – 714.384.7526 sales@agdistributorsllc.com www.agdistributorsllc.com 24 Contact Information
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