1. Tumor Board: Multidisciplinary Approach to Rare Breast Lesions Moderator: Aysegul A. Sahin, MD Panelists: Bruce Haffty Kelly K. Hunt Liane Philpotts Kalliopi P. Siziopikou Debu Tripathy ASBD-SIS 2014 World Congress on Breast Healthcare

2. 48-year old female presents with a palpable breast mass. She has a strong family history of breast cancer. Physical examination reveals a 2.5 cm mass, not fixed to overlying skin or underlying chest wall. Case #1

3. Courtesy of Dr. W. Yang

4. Case #1 Courtesy of Dr. W. Yang

5. Case #1 CNB reveals spindle cell malignant neoplasm cytokeratin

6. Case #2 48-year old woman had a stereotactic CNB of pleomorphic calcifications identified on screening mammogram.

7. Case #2

8. Dx: Pleomorphic Lobular Carcinoma in situ Case #2 E-cadherin

9. Case #2

10. Case #3 68-year old woman with history of myocardial infarct was found to have punctate calcifications associated with 1 cm left breast density on annual screening mammogram. Stereotactic CNB revealed invasive ductal carcinoma grade 2, ER+, PR+, Her2 -.

11. Case #3 Segmental resection and SLN biopsy was performed. 1.1 cm IDC, grade 2, no LVI Margins free (closest margin 0.5 cm)