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Thoracic Surgery Innovations
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Innovations VATS LVRS Chemotherapy Radiotherapy PET Small Cell N2
Stents & Lasers Stapler In Oesophagogastrectomy Epidural SVC stents
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VATS Sympathectomy Pleurectomy Lobectomy Biopsy mass lung
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Pneumothorax
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Pleurectomy VAT Muscle sparing Mini Full Thoracotomy
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VAT Lobectomy
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Biopsy Lung / Pleura
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LVRS
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LVRS
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LVRS Criteria Dyspnoeic on daily activities Age < 75
No bullae > 5cm Generalised emphysema with regional heterogeneity TLC > 125% FEV1 < 30 % PaCO2 < 50 mmHg, PaO2 > 40 mmHg on air No CAD or Pulmonary hypertension Steroid < 15 mg/day
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LVRS Unilateral / Bilateral Thoracotomy / Sternotomy / VAT
Role of Physio
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Chemotherapy and Radiotherapy
Preoperative Neoadjuvant Operative Postoperative Adjuvant
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Chemotherapy Numerous agents Adjuvant Neoadjuvant Stage IIIA (N2)
Stage II (T2N0) ? Role in N2 disease All oat cell Neoadjuvant Stage IIIA (N2) If respond are resected No residual tumour at surgery means prolonged survival Experimental
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Radiotherapy External beam external rays
Single / multiple beam / Fraction No Brachy local ie intra bronchial Interstitial directly into tumour Intra cavity in bronchus Adjuvant Postoperative Neoadjuvant Preoperative
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Radiotherapy Primary treatment Adjuvant for N1 / N2 Stage 1 and 2
Refuse or unfit for surgery Failure 30 % stage 1 (T1N0), 70% stage 2 (T2N0) 5 year survival 5 to 40% Adjuvant for N1 / N2 Reduces rate local recurrence Survival unchanged ? Role in +Ve resection margins
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Radiotherapy Neoadjuvant Palliative Brachytherapy
T3 Pancoast prior to surgery Palliative Symptomatic relief Pain, haemoptysis, bronchial, SVC obstruction Bone met pain Brachytherapy Local application high local dose
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Chemotherapy and Radiotherapy
Adjuvant Neoadjuvant Sequential / concurrent / alternating Good performance status Not standard practice May increase risk surgery
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PET 2-(fluorine-18) fluo-2-deoxy-D-glucose (18-FDG)
18-FDG competes with glucose for facilitated transport into tumour cells and also competes with glucose for phosphorylation by hexokinase Positive and negative predictive power
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Small Cell Lung Cancer
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Small Cell All need : Mediasteinoscopy CT head Bone scan
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Pre operative N2 Young patients Pre op chemo downstage No evidence
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Stents & Lasers Malignant terminal conditions that are inoperable
Benign inoperable conditions
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Tracheal obstruction-malignant - Pre and post Nd:Yag laser
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Left main bronchus extensive squamous cell carcinoma
Metal stent in left main
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Stapler In Oesophagogastrectomy
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Epidural Pain Poor PFTs Cardiac history Contraindications Low risk
On anticoagulants Consent Anatomical Infective
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SVC Stents
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Any Questions ?
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Next Week 2nd March Inotropes ITU seminar room
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