1. www.cpinmotion.dk Reliability of Gait Deviation Index in children with spastic cerebral palsy Helle Mätzke Rasmussen, Dennis B. Nielsen, Niels W. Pedersen, Søren Overgaard, Anders Holsgaard-Larsen Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, and Department of Clinical Research, University of Southern Denmark, Odense,

2. www.cpinmotion.dk Disclosures Related to present study – Grant from University of Southern Denmark (HMR); Odense University Hospital Research grants 2012 (AHL), the Region of Southern Denmark Research grants and Ph.D. Grants 2012 (AHL), the Physiotherapy Praxis Foundation (HMR), Ludvig and Sara Elsass Foundation (AHL) and The Danish Physiotherapy Research Fund 2013 (HMR). – No conflicts of interest (DBN, NWP, SO) Outside present study – Board memberships (Finalized): Eli Lilly Denmark, Advisory board: Fostero (SO); MSD: Advisory board : NSAID (SO); Mundipharma International Ltd (SO) – Investigator (Finalized) Sanofi-aventis Denmark A/S (SO) – Principal Investigator (Currently) Eli Lilly (SO) – Grants to Institution: Biomet DK and Biomet Inc: DePuy and Protesekompaniet (SO); Zimmer (SO, DBN, NWP, AHL, HMR)

3. www.cpinmotion.dk 3-diemensionel ganganalyse Schwartz MH et al. (2008)

4. www.cpinmotion.dk Gait Deviation Index GDI Kinematic variables Pelvic X 3 Hip x 3 Knee x 1 Foot x 2 100 Point = Reference group 10 Point = 1 SD 0° 20° Plantar / Dorsal flexion Step 100%0%

5. www.cpinmotion.dk Validity and reliability Construct validity has previously been shown – FAQ, GMFCS, GMFM, GGI, CP Subtype Reliability – Not investigated in children with CP Schwartz MH et al. (2008), Molloy M et al. (2010), Massaad et al. (2013)

6. www.cpinmotion.dk Materials 18 Children Subtype 10 Unilateral CP 8 Bilateral CP GMFCS 9 GMFCS level I 9 GMFCS level II Age Age 5 – 12 years Mean age 7.8 (SD 2.11)

7. www.cpinmotion.dk Method Test Team A Retest Laboratory Team B Team C + TestRetest + TestRetest +

8. www.cpinmotion.dk Results - Bland-Altman plot Mean – 0.3 SEM 95%

9. www.cpinmotion.dk Conclusion and perspective Good reliability Holds promise for the use of Gait Deviation Index as outcome measure in clinical research.

10. www.cpinmotion.dk Thanks! Lotte Slot Jensen Dennis Brandborg Nielsen Funding Odense Universitets frie forskningsmidler 2012 Region Syddanmarks Forskningspulje 2012 og Ph.d. pulje 2012 Fysioterapi Praksis Fonden Ludvig og Sara Elsass Fond Danske fysioterapeuters Forskningsfond Syddansk Universitet