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2. Copyright © 2009 Massachusetts Medical Society. All rights reserved. Published by Massachusetts Medical Society. 2 Table 1 Long-Term Outcome Associated with Early Repolarization on Electrocardiography. Tikkanen, Jani; Anttonen, Olli; Junttila, Juhani; Aro, Aapo; Kerola, Tuomas; Rissanen, Harri; Reunanen, Antti; Huikuri, Heikki New England Journal of Medicine. 361(26):2529-2537, December 24, 2009. Table 1 Characteristics of the Subjects at Baseline.

3. Copyright © 2009 Massachusetts Medical Society. All rights reserved. Published by Massachusetts Medical Society. 3 Table 2 Long-Term Outcome Associated with Early Repolarization on Electrocardiography. Tikkanen, Jani; Anttonen, Olli; Junttila, Juhani; Aro, Aapo; Kerola, Tuomas; Rissanen, Harri; Reunanen, Antti; Huikuri, Heikki New England Journal of Medicine. 361(26):2529-2537, December 24, 2009. Table 2 Unadjusted and Adjusted Relative Risk of Death, According to J-Point Elevation.

4. Copyright © 2009 Massachusetts Medical Society. All rights reserved. Published by Massachusetts Medical Society. 4 Figure 1 Long-Term Outcome Associated with Early Repolarization on Electrocardiography. Tikkanen, Jani; Anttonen, Olli; Junttila, Juhani; Aro, Aapo; Kerola, Tuomas; Rissanen, Harri; Reunanen, Antti; Huikuri, Heikki New England Journal of Medicine. 361(26):2529-2537, December 24, 2009. Figure 1 Kaplan-Meier Curves for Death from Cardiac Causes and from Arrhythmia in Subjects with J-Point Elevation. Subjects with J-point elevation of more than 0.2 mV in the inferior leads on standard 12-lead electrocardiography had a markedly elevated risk of death from cardiac causes, as compared with those without an early-repolarization pattern (<0.1 mV), with an unadjusted relative risk of 3.52 (95% confidence interval [CI], 2.18 to 5.68; P<0.001) (Panel A). The same subjects had an unadjusted relative risk of death from arrhythmia of 3.94 (95% CI, 1.96 to 7.90; P<0.001) (Panel B).

5. Copyright © 2009 Massachusetts Medical Society. All rights reserved. Published by Massachusetts Medical Society. 5 Figure 2 Long-Term Outcome Associated with Early Repolarization on Electrocardiography. Tikkanen, Jani; Anttonen, Olli; Junttila, Juhani; Aro, Aapo; Kerola, Tuomas; Rissanen, Harri; Reunanen, Antti; Huikuri, Heikki New England Journal of Medicine. 361(26):2529-2537, December 24, 2009. Figure 2 Baseline Electrocardiograms of Two Male Subjects with J-Point Elevation of More Than 0.2 mV in the Inferior Leads. In two subjects with J-point elevation of more than 0.2 mV in the inferior leads, Subject 1 has a slurred elevation (arrows) and Subject 2 has a notched elevation (arrows). Both subjects died from arrhythmia during the follow-up period.

6. Copyright © 2009 Massachusetts Medical Society. All rights reserved. Published by Massachusetts Medical Society. 6 Table 3 Long-Term Outcome Associated with Early Repolarization on Electrocardiography. Tikkanen, Jani; Anttonen, Olli; Junttila, Juhani; Aro, Aapo; Kerola, Tuomas; Rissanen, Harri; Reunanen, Antti; Huikuri, Heikki New England Journal of Medicine. 361(26):2529-2537, December 24, 2009. Table 3 Adjusted Relative Risk of Death from Cardiac Causes in the Secondary Analysis.