1. Dyspepsia: an underestimated problem among end-stage renal disease patients Paulo Santos Federal University of Ceará, Brazil

2. Highly prevalent Great impact on quality of life

3. Prevalence In the literature: between 50% and 70% VanVlem et al Am J Kidney Dis 2000; 36:962 Cano et al Am J Gastroenterol 2007 102:1990

4. Impact on Quality of Life Santos et al. Brazilian Congress of Nephrology 2012

5. What is dyspepsia?

6. Constellation of symptoms – Upper abdominal pain; Nausea; Vomiting; Upper abdominal bloating; Early satiety Tack et al. Gastroenterology 2006; 130:1466

7. WHY? I.Gastric emptying delay II.Hypervolemia

8. WHY? I.Gastric emptying delay II.Hypervolemia

17. Clinical implications I.It is very easy to search for symptoms of dyspepsia, so it should be done often II.Our finding raises the question about the main role of prokinetics in dyspepsia cases

18. WHY? I.Gastric emptying delay II.Hypervolemia

19. WHY? I.Gastric emptying delay II.Hypervolemia

20. Volemic status

23. Clinical implications I.Functional dyspepsia could be an alert of the need to revise the prescribed dry-weight of patients on HD II.Dyspeptic symptoms could be another tool to help estimate the optimal dry weight of patients on HD

24. IMPACTS ON NUTRITIONAL STATUS?

27. Clinical implication I.Screening of dyspeptic symptoms can be used as a tool for identification of patients on HD who are at risk of malnutrition

29. prsantos@fortalnet.com.br prsantos@fortalnet.com.br www.drpaulosantos.com.br