1. AP Biology (An Introduction)
Mr. Boswell
Room 208

2. Overview – 1st Day
1. Attendance 2. Introduction to 21st century science (20 min.) 3. Introduction to AP Biology & Mr. Boswell (15 min.) 4. Summer Project Insights (5 min.)

3. Baby gorilla reacts to a cold stethoscope

4. Introduction to
21st Century SCIENCE

5. 20th Century SCIENCE
The 20th century was the domain of the physical sciences. Incredible discoveries were made, and then converted into applications for commerce and military.
How many of these chaps are you familiar with?

6. Alba – GFP bunny
Expired in 2002
“Transgenic art”
AP Lab #6

7. Human Genome Project Completed in 2003 Cost $2.7 billion
Joint Genome Institute (Walnut Creek, CA)
Sequenced entire human genome (DNA)
Cost $2.7 billion
2004, Celera (J. Craig Venter) = $300,000,000 (11%)
2010, Illumina (San Diego, CA) = $14,500 (0.0005%)
2013, $1,000 or less
21st century = Molecular Biology
If you do not agree, consider but one example, the sequencing of a human genome.

8. 21st Century Therapies Gleevec – Chronic Myelogenous Leukemia
1 pill a day
Sprycel & Tasigna
In 2010, Oncept DNA Vaccine
Canine Oral Melanoma
Transdermal application
June 2010, “siRNA ‘Cure’ for Ebola?” (Geisbert et al.)
May 20, 2010, first “synthetic” life form is created

9. 2013 Biotechnology
U. Pitt group produces human heart cells from iPSCs that spontaneously beats on its own
Human Liver tissue regrown from iPSCs
Surgeons at Duke University implanted a bioengineered blood vessel into patient
Netherlands researchers produced lab-grown burger from ONLY cow stem cells.

10. Stanford University Newest department: Bioengineering
Stanford has a $1,000,000,000 commitment
Last department added: 23 years ago
Computer Science
Silicon Valley
MIT
Broad Institute of MIT & Harvard (2004)
Koch Institute for Integrative Cancer Research (2008)

11. Introduction to AP BIology

12. 2013 AP Biology Results  Pass Rate = 88% “5”s = 10% Students = 100
There will be zero 1s or 2s this year.

13. Why this class is difficult…
1. Honors Biology ≠ AP Biology
-- Biology knowledge base may be deficient
Chapters (over 1,000 pages)
3. 3 credits vs. 8 credits for college
4. Significant Mathematics focus (Chi-Square Test, etc.)
5. Application & Evaluation Test Questions

14. Why this class not difficult…
1. Clear expectations
Vocabulary & Objectives
2. Information is readily available
3. Course Materials sourced from 5 Biology textbooks
4. Course materials are easily accessible
5. Few complicated concepts

15. What is a College Level Course?
Student-Driven Learning
“students are expected to work independently outside the class”
Role of teacher is to highlight some important points
Will NOT cover every concept in class
Homework will consist of videos or readings that need to be completed before class

16. Q1 Biochemistry Q3 Q2 Q4 Cells Energetics
Classical & Molecular Genetics
3 Lab Exercises
CHAPTERS [17] Q3
Animal & Human Physiology
Ecology
Free-Response Questions
12 Lab Exercises
CHAPTERS [9] Q2
DNA Technology & Genomics
Evolution
Plant Physiology
7 Lab Exercises
CHAPTERS [14] Q4
Review for AICE Papers &
AP Exam

18. Class Discussions You WILL be called on to attempt an answer
I want to hear what you have to say
Please make all questions and comments relevant to the content discussion
If your question is off topic, write it down and ask it later

19. Introduction to Mr. Boswell

20. AP Biology Background Undergrad: Philosophy & Biochemistry
Masters: Medical Economics & Epidemiology
HHMI (Howard Hughes Medical Institute) Cohort
Inaugural Fellow University of Florida
AP Summer Institute (2007, 2008, 2009, & 2012)
AP Fellows Grant & Stanford University
AP Annual Conference (2008, 2012)
AP Biology Review at 2012 National Science Bowl
Broward County 2013 AP Biology Review
Test Item Contributor for 2014 AP Biology Exam

21. SUMMER PROJECT &
Tests

22. Summer Project The worksheet is due by 11:59pm on 8/23/13to
The Online Assessments must be complete by 11:59pm on 8/23/13
In Class Assessment:
Biology – Wednesday (8/21/13)
Chemistry – Friday (8/23/13)

23. BUM Insights Nucleoid / Cell Wall present in bacterial cells?
Prokaryotes?
Does Golgi Body (Apparatus) contain ribosomes?
Need to know the number of chromosomes, chromatids, and chromatin in each stage of mitosis
What is the longest phase of the cell cycle?

24. BUM In Class Assessment
30 Questions
8 Multiple Correct (Select ALL of the following…)
22 Multiple Choice
Spread evenly between 3 topics covered in the BUM
About ½ of the questions are application
Review the Formative Assessment & Worksheet
Think about what would happen if an organelle or molecule were to malfunction.
Consider various pathologies of cell organelles, molecular properties of water, and cell cycle

25. CUS Insights Polar means it can dissolve in ______
Amino acids can act as BOTH an _____ and a _____
Which functional groups act like acids? Bases?
Learn Polar bonds and polar molecule rules
Which molecules exhibit Van der Waal forces?
Which functional groups have a carbon double bonded to an oxygen?

26. CUS In Class Assessment
26 Questions
16 Multiple Choice
10 Multiple Correct
Score is out of 25 (one question is effectively Xtra credit)
Review the Formative Assessment & Worksheet
Functional groups are important

27. Upcoming Tests 8/28/13 – First Test 10/14/13 TEST Q1-01 (15%)
Covers Only Chapters 3-5
Focus is on CH 5
Application & Pathologies
10/14/13
Cumulative Test (20%)
Afterschool on Monday 10/14/13
110 students in Auditorium & 60 students in Media Center